They don't bother me, though in some scenes on TV shows I find them inappropriate. Like in that episode of Boy meets World where Cory left 5 year old Morgan alone and she broke a window and ran away to hide, and he came home and thought she was kidnapped. Hours later the parents come home, find the window broken, Cory tells them he'll pay for it. His dad asks 'how are you going to do that?' and Cory says 'well I would tell you but the shouting that would ensue would wake up my little sister, who thank God is still alive'. To me, that was a bad place to put a laugh, because considering it from his view point, that was a very serious situation.
Then there are times I think they could USE a laugh, like in the episode of Roseanne when she and Dan are having the mother of all battles and destroying everything. And he says 'why don't you tell me how to clean up all this crap! that you call decorating?' and he throws everything on the floor and she says, 'Okay, I will, I want you to pick them all up using your ASS, and start with the pointy things!' That COULD have used a laugh in it.